ABSTRACT:
Myasthenia Gravis (MG) is a chronic autoimmune neuromuscular disorder characterized by fluctuating skeletal muscle weakness and fatigability. Due to its variable presentation and episodic course, MG poses significant challenges in diagnosis, treatment adherence, and long-term care. Nurses play a vital role in early recognition, monitoring disease progression, preventing complications, and providing patient-centered education. This systematic review aims to synthesize available evidence on nursing considerations in the management of adults with Myasthenia Gravis, with emphasis on clinical care, prevention of complications, psychosocial support, and multidisciplinary coordination. A systematic literature search was conducted using PubMed, Google Scholar, National Institutes of Health (NIH), and World Health Organization (WHO) databases. Articles published in English between 2000 and 2025 were reviewed. Keywords included “Myasthenia Gravis,” “adult nursing care,” “autoimmune neuromuscular disorders,” and “nursing management.” Peer-reviewed articles, clinical studies, guidelines, and authoritative reports were analyzed. Myasthenia Gravis is primarily mediated by antibodies against acetylcholine receptors or related neuromuscular junction proteins, resulting in impaired neuromuscular transmission. Major nursing concerns include respiratory monitoring, medication management, prevention of myasthenic crisis, fatigue management, nutritional support, and psychological care. Patient education and multidisciplinary collaboration were essential in improving treatment adherence and quality of life. Nursing care is fundamental to the comprehensive management of adults with Myasthenia Gravis. Early identification, vigilant assessment, individualized interventions, and continuous education significantly enhance patient safety, functional independence, and overall quality of life.